Heat Generation in Irradiated Gold Nanoparticle Solutions for Hyperthermia Applications
نویسندگان
چکیده
Gold nanoparticles (GNP) aided hyperthermia has demonstrated promising results in the treatment of cancer. However, most existing investigations focus only on extinction spectra GNP solutions, few reported actual heat generation capability these solutions to estimate their real potential in-situ treatment. In this study, impact clustering optical properties and heating aggregates acidic have been investigated. It was found that localized could be significantly enhanced (to up 60.0 °C) when were illuminated by a near infrared light source at 1.7 W/cm2. addition, thermography imaging can detect surface temperature during thermal treatment, leaving distribution inside tissues unknown. To overcome limitation, absorbed energy NIR irradiation obtained computationally coupling P1 approximation with DDA calculation predict change solutions. due accumulation dissipation heat, some local areas showed higher increase hot spots being connected merged over time.
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ژورنال
عنوان ژورنال: Processes
سال: 2021
ISSN: ['2227-9717']
DOI: https://doi.org/10.3390/pr9020368